In this event, Professor Koleske will discuss recent advances in current understanding of the genetic bases of schizophrenia, a debilitating neurodevelopmental disorder. Then he will discuss ongoing efforts, including work in his own lab, to understand what do schizophrenia risk genes do and how we are trying to use this knowledge to identify new treatments for the disorder.
The language of the event will be English and Chinese.
Registration and Payment
RMB 20 for students; RMB 60 for Yale alumni; RMB 80 for others.
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6:30 PM - 7:00 PM
7:00 PM - 8:30 PM
Talk and Q&A
Professor of Molecular Biophysics and Biochemistry at Yale University
Anthony J. Koleske is an expert in understanding the biochemical mechanisms that control dendrite and synapse development, maturation, and stability. After receiving a B.S. in Biochemistry and Molecular Biology at the University of Wisconsin-Madison, Dr. Koleske performed his Ph.D. studies with Richard Young at the Whitehead Institute/Massachusetts Institute of Technology. As a student, Dr. Koleske discovered the RNA polymerase II holoenzyme, an important advancement in understanding how gene transcription is turned on. Dr. Koleske went on to do a postdoctoral fellowship with Nobel Laureate Dr. David Baltimore at M.I.T., where he began his work studying cellular functions of Abl family kinases, which his laboratory has shown are essential regulators of the cytoskeleton in diverse cell types. Dr. Koleske joined the Department of Molecular Biophysics and Biochemistry at Yale University in 1998, where he currently is Professor and holds a joint appointment in the Department of Neuroscience.
Dr. Koleske is the recipient of numerous awards including a Jane Coffin Childs Postdoctoral Fellowship, Special Fellowship and Scholar Awards from the Leukemia and Lymphoma Society, a NARSAD Young Investigator Award, and an Established Investigator Award from the American Heart Association. He has served widely on review panels, including terms as Chair of the Basic Science Study Section for the American Heart Association and the Neurodifferentiation, Plasticity, Repair, and Rhythmicity Study Section of the NIH. He currently directs the combined Ph.D. programs in the Biological and Biomedical Sciences at Yale, the China Scholarship Council-Yale World Scholars Program.